History of Present Illness:  The patient is a 72 year old black female with a chief complaint of nausea and vomiting, weakness, and shortness of breath.

Past Medical History: 

  • Breast Cancer with lumpectomy on the right side and a lymph node dissection.
  • Hypothyroidism

Social HistoryPatient does not smoke, but uses tobacco occasionally.  No alcohol or IV drugs.

Medications Prior to Admission:  Levothroxine and Avalide

Nuclear Medicine Studies:  Patient has a large substernal thyroid and shortness of breath.  A parathyroid scan was ordered to rule out parathyroid adenoma.  24.4 mCi of Tc-Sestamibi was injected I.V. and and the thyroid was scanned with standard projections at 15 minutes, 90 minutes, and 3 hours.

15 minutes

90 minutes

3 hour image

There is a large area of increased uptake in the neck especially on the left which extends inferiorly into the mediastinum.  This is consistant with a large goiter and correlates with a CT scan done previously.  On the 3 hour scan, a small focal area of increased tracer activity is seen in the left side of the neck which may represent a parathyroid adenoma, however because of the large thyroid enlargement on the left this finding is not conclusive.

A cardiac output study was performed and it demonstrated diffuse LV hypokinesia with an ejection fraction of 20% (normal >50%) and a dilated left ventricle.

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Images courtesy of UAMS Dept of Nuclear Medicine.